Researchers at the University of Arizona have reached a new theory of previous results on the causes of Alzheimer's disease. According to this, the disease is caused by the genetic changes caused by stress in neurons.
Alzheimer's disease, in which more than fifty million people in the world suffer from an inadvertent disease that affects the brain with memory disorder and dementia. Although it is clear that the brain cells are destroyed by the accumulation of some proteins, the research of the disease is one of the most difficult areas of research, also known as the Dream Cemetery, due to its complications, a dead end. And despair.
Arizona researchers started with health databases and modern research, especially from a study on the progress of the disease in 2022.
What happens in nerve cells is that the disease completely changes its function: biochemical processes change, communication with other neurons, abnormal proteins, appeared, Tauces and Beta-amyloids appeared. However, it is not clear what leads to this change.
Try to seize the first step
According to the new theory, the process is run by cell stress. Cells respond to conditions that are difficult to work by creating proteins and RNA-A A healthy answer that protects internal balance. According to American researchers, the root of the problem is that these particles remain after stress, including communication between the nucleus that contains genetic seeds and the rest of the cell.
If our proposal is going to the conclusion of the cell plasma and the nucleus, and this leads to a wide range
Brain researcher Paul Coleman explained.
Genetic expression is the process in which the biological plans carry the DNA from the nucleus to different parts of the cell and build in the form of functional proteins. In the case of emergency due to stress, these genes expressions become 90 percent, in thousands of cases. At this point, the cell begins to die and appear in plaques and knots.
It has not yet been proven whether the thought line is actually working. The researchers confirmed that they are not looking for new elements to develop the disease, but they were trying to provide the mystery in the system. Based on the proposed system, Alzheimer's disease begins with cell tension. What might be, it's also a question: genetic mutation, injury, infection, pesticides, minerals, air pollution, perhaps all, mix, or perhaps toxic proteins that appear as a result of stress.
According to Coleman, their studies are related to the current discussion when Alzheimer's disease begins, where the first component of the series of events can be found, and the point where the disease can be prevented.
((Science alert))